2. Signaling Pathways
  3. Immunology/Inflammation
  4. Interleukin Related
  5. IL-8 Isoform
  6. IL-8 Agonist

IL-8 Agonist

IL-8 Agonist (1):

Cat. No. Product Name Effect Purity
  • HY-175013
    CDK6/9-IN-2
    		Agonist
    CDK6/9-IN-2 is a highly active dual inhibitor of CDK6 (IC50 = 15 nM) and CDK9 (IC50 = 22 nM). CDK6/9-IN-2 is selective for CDK2, CDK8, and CDK11. CDK6/9-IN-2 inhibits the proliferation of HaCaT cells induced by IFN-γ/TNF-α and suppresses the STAT3 pathway and the expression of inflammatory factors. CDK6/9-IN-2 can alleviate psoriatic dermatitis and is useful in psoriasis research.